Cardiac mechanics

Cardiac mechanics research is dedicated to the understanding how individual heart-muscle cells contribute to the contractile function of the complete heart, both in healthy and in pathological conditions. We are particularly interested in the adaptation of the heart muscle to changes in mechanical load, for instance induced by cardiac arrest or pacemakers. Functional MRI techniques, like MR-tagging, are developed and applied to assess pathology in electrically conductive and contractile pathologies. We develop and validate powerful computational models for electrical conductance, excitation and muscle contraction of the complete heart to extend diagnostic measurements and the planning of treatment modalities.

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