Biopolymers in cells are continually in thermal motion. Their interactions are often fairly well known though biologically contingent (i.e. sensitive to detail of biological importance). The aim is to develop theories of biomacromolecular systems dealing with both these issues, often using argumentation based on statistical physics. General focus is on proteins and double-stranded DNA, both in vitro and in vivo.
Themes are: statics and dynamics of DNA packaging in phages; compaction of supercoiled genomes in bacteria; transport through ion channels; interactions between proteins; physico-chemical aspects of gene expression (e.g. via H-NS proteins); polymer depletion by proteins.
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