Micro-fluidic systems are projected in a variety of new exciting applications for instance in the pharmaceutical, fine and (even) bulk chemicals industries and in the field of medical technology. It can be anticipated that completely new (cheap and robust) and very sophisticated fabrication technologies and (efficient) multi-scale hybrid particle based computational tools are required to fully explore and utilize the potential of these devices. The development of micro-manufacturing methods has made it possible to produce structures at micrometer (smaller than a millimeter) and even smaller. Such structures offer the possibility of miniaturization of fluidic systems to manipulate (complex multiphase) fluids including complex physical and/or chemical transformations with much better (ultimate) control of all critical process steps. Prediction of the relation between product properties and process variables is a key ingredient. Similar challenges exist in the field of materials science for the accurate prediction of the properties of novel composite and/or micro-structured materials where interactions at very small length scales (at micro or meso scale) need to be captured accurately in order to predict the macroscopic material properties with confidence.
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